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The enzyme cytochrome P450 (CYP1B1) has been implicated in cancer improvement and development. In this examine, the outcomes of PA, EA, POMx, and PJ on the expression of androgen-synthesizing enzyme genes and the androgen receptor were being also measured. 5. Yuan T, Ma H, Liu W, et al.: Pomegranate's Neuroprotective Outcomes against Alzheimer's Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites. 15. Kasimsetty SG, Bialonska D, Reddy MK, et al.: Outcomes of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate most cancers cells. In a analyze claimed in 2009, the outcomes of pomegranate metabolites on CYP1B1 activation and expression in CWR22Rv1 prostate most cancers cells had been examined. five. Ramachandran C, Wilk BJ, Hotchkiss A, et al.: Activation of human T-helper/inducer cell, T-cytotoxic cell, B-cell, and organic killer (NK)-cells and induction of purely natural killer mobile action from K562 continual myeloid leukemia cells with modified citrus pectin. Research research in the laboratory have examined the outcomes of pomegranate on many prostate cancer mobile traces and in rodent versions of the ailment. The outcomes of pomegranate on prostate cancer have been examined employing a quantity of rodent products of the ailment.